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CAd3-ZEBOV
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
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Contents
β’ Eigenschaften
β’ Einzelnachweise
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
Eigenschaften
cAd3-ZEBOV ist ein viraler Vektor, der auf dem Schimpansen-Adenovirus Typ 3 (chAdV3) basiert. Zur Erzeugung des Impfstoffs wurde in dessen Genom ein Gen aus dem Ebolavirus eingefΓΌgt, welches die viralen Glykoproteine (GP) des Zaire-Ebolavirus und des Sudan-Ebolavirus codiert. Die Verabreichung erfolgt durch intramuskulΓ€re Injektion. cAd3-ZEBOV wurde von GlaxoSmithKline entwickelt. Der Impfstoff wurde ab September 2014 in klinischen Studien untersucht.cite-ref-1[1]cite-ref-2[2]
Einzelnachweise